Filtration / retention enrichment membrane

Filtration / retention enrichment membrane

Filtration and retention concentrate small particles from a larger liquid sample onto one membrane, ready for microscopy, fluorescence or PCR / NGS preprocessing.

Route value

Turn larger-volume samples into a membrane ready for detection

As carrier liquid passes through the filtration membrane, bacteria, cells and other small particles are retained and concentrated at the surface. With matched optical clearing the membrane can enter microscopy, or connect to lysis, PCR and NGS library-preparation workflows.

A broader sample entry point
Concentrate particulate targets from liquid, environmental and industrial samples with membrane and pretreatment choices matched to the project.
Fewer avoidable transfers
Compatible workflows can use the enriched membrane directly, helping retain low-abundance targets already captured at the surface.
One membrane, multiple pathways
Connect microscopy, fluorescence, lysis, PCR or NGS preprocessing from the same enrichment interface.

Technology principle

As carrier liquid passes through the filtration membrane, its pore structure retains bacteria, cells and other small particles, concentrating low-abundance targets from a larger sample volume within a compact surface area. Matched clearing medium reduces light scattering caused by air in the pores while targets remain at the surface for microscopy; the enriched membrane can also connect directly to lysis, PCR amplification and NGS library preparation with fewer avoidable elution and transfer steps.

Workflow connection

  1. Step 1Sample pretreatment

    Match the sample and membrane

    Match pore size, surface wettability and pretreatment to the sample matrix, target particles and intended detection pathway.

  2. Step 2Enrichment

    Retain and concentrate targets

    Let carrier liquid pass while target particles are retained within a compact membrane area, so low-abundance targets enter downstream detection at a higher concentration.

  3. Step 3Microscopy

    Use the membrane directly

    Compatible workflows can clear and observe the enriched membrane, or place it directly into lysis and molecular preprocessing with fewer elution and recovery steps.

  4. Step 4NGS preprocessing

    Connect multiple downstream methods

    Connect microscopy, fluorescence, PCR, NGS or another analysis route from the same enrichment interface.