Membrane-enrichment technology platform overview

Membrane-enrichment technology platform overview

See why the membrane can concentrate and clear for observation, how to choose between two routes and how each connects to downstream detection.

What this guide explains

  1. Optical clearing

    Understand why a porous membrane appears white and how matched clearing makes on-membrane observation possible.

  2. Two enrichment routes

    Compare centrifugation / embedded adsorption with filtration / retention and choose from the sample, target and method.

  3. Downstream interfaces

    See how the enriched membrane connects to morphology, fluorescence, PCR / NGS and other project-matched methods.

Document

When cells, bacteria or small particles are dispersed through a larger sample, a direct aliquot may leave much of the available target outside the test. Tianqi's platform first uses centrifugation / embedded adsorption or filtration / retention to concentrate targets within a compact ultra-thin membrane area; typical workflows provide approximately 20–100× enrichment depending on sample volume and process conditions. A porous membrane normally appears white because air in its pores scatters light. With a matched clearing medium, the membrane becomes more optically transmissive while targets remain at the surface for bright-field, morphology or compatible fluorescence observation. The sandwich-cup route supports standardised slide preparation, staining and review, while the filtration route can handle water, culture media and other method-compatible liquid samples; the enriched membrane can also move directly into lysis, PCR amplification or NGS library preparation without first eluting targets back into liquid. This reduces avoidable tube changes, elution, recovery and repeat slide preparation, and creates a configurable entry point for clinical laboratory, life-science, environmental, industrial and joint-development contexts.