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CONFIGURABLE MEMBRANE ENRICHMENT
Enrich first. Detect with substantially greater sensitivity.
Concentrate low-abundance cells, bacteria and small particles from sputum, water, culture media or another sample by centrifugation / embedded adsorption or filtration, then connect the enriched membrane to microscopy, fluorescence, PCR / NGS or environmental and industrial analysis.
ENRICHMENT FIRST
Concentrate and retain targets at the membrane surface first, then connect morphology, fluorescence, PCR / NGS, or environmental and industrial testing.
Principle schematic · particle numbers and proportions do not state concentration or recovery rate
MEMBRANE PROPERTIES
Typical workflows reach about 20–100× enrichment depending on sample volume and process conditions. With a micron-scale ultra-thin membrane, adjustable pore size, ultra-low fluorescence background and clearing for observation, targets are more concentrated, interference is lower and downstream detection finds them more easily.
01 / 07 · Enrichment by sample volume
20–100×
Achievable enrichment
A micron-scale ultra-thin membrane forms a compact interface for targets; depending on sample volume the platform reaches about 20–100× enrichment, bringing targets more concentrated into downstream detection.
02 / 07 · Retention matched to the target
0.22–0.45μm
Pore-size range in published materials
Pore size is chosen by target size and sample condition, so targets stay at the membrane while carrier liquid passes and unrelated material interferes less.
03 / 07 · Selectable surface properties
Hydrophilic / hydrophobic
Two surface-property directions
Hydrophilic, hydrophobic and other surface options suit different sample conditions and improve contact between the sample and the membrane and the retention of targets.
04 / 07 · Stable through processing
3media
The membrane tolerates the acid, alkali and organic-solvent conditions the workflow requires, so the enrichment interface connects to digestion, staining and other processing.
05 / 07 · Compatible with direct observation
0extra transfers
Compatible direct-observation workflows
Clearing makes the pore network disappear under the microscope; compatible workflows observe targets on the membrane without further elution or transfer, reducing handling loss.
06 / 07 · Fluorescence and bright-field microscopy
Ultra-low fluorescence
can be cleared
Direct observation on the membrane, no elution or transfer
Suitable membrane types combine an ultra-low fluorescence background with clearing by matched treatment; targets enriched on the membrane can go straight to fluorescence or bright-field microscopy without first being eluted or transferred.
07 / 07 · Thin but stable
Positive / negative pressure
Supports enrichment and post-processing
Mechanical stability supports filtration, transfer and post-processing while keeping the membrane flat and intact as the workflow requires.
TWO ROUTES
Choose centrifugation / embedded adsorption for smaller or standardised batch workflows, and evaluate filtration / retention for larger liquid volumes. Both routes concentrate targets at the membrane surface, with membrane type and conditions set by sample, target and detection method.
ROUTE A · Centrifugal action
After matched pretreatment, the sample enters the sandwich cup, where centrifugation and embedded adsorption concentrate targets at the ultra-thin membrane, suited to standardised slide preparation and review.
STRUCTURE · Sandwich cup
A one-piece blue long-wing cap, the single slide inside it with its round ultra-thin membrane facing the cup, a separate seal and a clear cup assemble layer by layer into one enrichment unit.
ENRICHED MEMBRANE
Once the slide is half withdrawn, the round membrane at its centre comes out with it; the targets enriched on it continue to clearing, slide preparation, staining and review.
Red markers only show where enrichment happens, not the form or number of targets.
Explore the centrifugal routeROUTE B · Direct filtration
After matched pretreatment, larger liquid volumes pass through the filtration membrane, which concentrates cells, bacteria or small particles at its surface for microscopy or molecular preprocessing.
FILTRATION
The upper part is the complete red-cap clear collection tube and the lower part the red slide-preparation device; the white disc faces outward and fits with the black filter end and the red barrel. The enriched membrane can go to microscopy or into lysis and molecular preprocessing.
Appearance is corrected against photographs; the internal channels and the white disc’s function follow the formal product documents.
Explore the filtration routeDOWNSTREAM INTERFACES
One enriched membrane can carry cells, bacteria and small particles into morphology and fluorescence observation, straight into lysis and PCR / NGS preprocessing, or into water, air and production-environment testing.
Keep cells, bacteria, fungi or other small particles on the membrane, then connect clearing, slide preparation, staining, microscopy, scanning and digital review.
Morphology applications 02With the ultra-low fluorescence background of suitable membranes, enriched cells, microbes or labelled particles go straight into a matched fluorescence workflow.
Configure fluorescence 03The enriched membrane goes straight into lysis, PCR amplification or NGS library preparation without first eluting targets back into liquid; each downstream method keeps its own steps.
Nucleic-acid preprocessing 04For surface water, process water, air and production environments, low-abundance microbes or particles are concentrated before microscopy, fluorescence or molecular detection.
Environmental and industrial usesEVIDENCE & RESOURCES
Tianqi Medical develops membrane materials, enrichment consumables and workflows as one platform that concentrates and retains targets at the membrane surface. Once enriched, the sample can connect to morphology, fluorescence, nucleic-acid or other methods with fewer avoidable transfer and elution losses.
Matched clearing medium reduces light scattering within a porous membrane while targets remain at its surface for observation.
Enrichment range, membrane properties and workflow outcomes are verified under their applicable sample and process conditions.
Core membranes, consumables, reagents, instruments and digital analysis form a connected product system.
ENRICHMENT FIRST · DETECTION NEXT
The enriched membrane interface can connect to morphology, fluorescence, nucleic-acid and other methods as needed. Our technical team can explain how the platform fits the existing workflow and which product system carries it forward.